Critical seeding density improves the properties and translatability of self-assembling anatomically shaped knee menisci

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Critical seeding density improves the properties and translatability of self-assembling anatomically shaped knee menisci.

A recent development in the field of tissue engineering is the rise of all-biologic, scaffold-free engineered tissues. Since these biomaterials rely primarily upon cells, investigation of initial seeding densities constitutes a particularly relevant aim for tissue engineers. In this study, a scaffold-free method was used to create fibrocartilage in the shape of the rabbit knee meniscus. The obj...

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ژورنال

عنوان ژورنال: Acta Biomaterialia

سال: 2015

ISSN: 1742-7061

DOI: 10.1016/j.actbio.2014.09.011